- Article (title, authors, journal, year and pages): Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression – Chen N-H.-Pharmacological Reports 2010 – 62 – 150-163
- Plant (scientific name of the main plant): Ganoderma lucidum
- WP4 reference member: Prof. Laura Maria Garcia Bermejo
- Plant/s used (if a phytocomplex from one or more plants are used):
- Formula used (if a phytocomplex from a formula is used):
- Purified molecules used (if single compounds are used): ganoderic acid T
- Disease/s: cancer
- molecular target/s and/or mechanisms investigated: inhibition of proliferation, inhibition of adhesion to ECM, induction of homotypic aggregation, inhibition of cell migration, down-regulation of the expression of matrix metalloproteinase-9
(MMP-9), inducible nitric oxide synthase (iNOS), and urokinase-type plasminogen activator (uPA).
- General quality score (mean ± SD): article not meeting inclusion criteria for evaluation
- Relevance score for TCM research (mean ± SD): article not meeting inclusion criteria for evaluation
