{"id":3090,"date":"2011-01-28T01:40:09","date_gmt":"2011-01-28T01:40:09","guid":{"rendered":"http:\/\/www.gp-tcm.org\/?p=3090"},"modified":"2022-04-29T01:48:54","modified_gmt":"2022-04-29T01:48:54","slug":"fructus-corni-suppresses-hepatic-gluconeogenesis-related-gene-transcription-enhances-glucose-responsiveness-of-pancreatic-beta-cells-and-prevents-toxin-induced-beta-cell-death-chen-cc-et-a","status":"publish","type":"post","link":"https:\/\/www.gp-tcm.org\/index.php\/2011\/01\/28\/fructus-corni-suppresses-hepatic-gluconeogenesis-related-gene-transcription-enhances-glucose-responsiveness-of-pancreatic-beta-cells-and-prevents-toxin-induced-beta-cell-death-chen-cc-et-a\/","title":{"rendered":"Fructus Corni suppresses hepatic gluconeogenesis related gene transcription, enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death \u2013 Chen CC et al. &#8211; Journal of Ethnopharmacology 117 (2008) 483\u2013490"},"content":{"rendered":"<p><\/p>\n<ul>\n<li>Article (title, authors, journal, year and pages):\u00a0<a href=\"http:\/\/www.sciencedirect.com\/science?_ob=ArticleURL&amp;_udi=B6T8D-4RYNMFW-1&amp;_user=121727&amp;_coverDate=05%2F22%2F2008&amp;_rdoc=1&amp;_fmt=high&amp;_orig=search&amp;_origin=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000010000&amp;_version=1&amp;_urlVersion=0&amp;_userid=121727&amp;md5=05a156e0b4fe2598f6d8cb049dd8d326&amp;searchtype=a\" target=\"_blank\" rel=\"noopener\">Fructus Corni suppresses hepatic gluconeogenesis related gene transcription,enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death<\/a>\u00a0\u2013 Chen CC et al. &#8211; Journal of Ethnopharmacology 117 (2008) 483\u2013490<\/li>\n<li>Plant (scientific name of the main plant): Cornus officinalis<\/li>\n<li>WP4 reference member: Prof. Enrica Bosisio<\/li>\n<li>Plant\/s used (if a phytocomplex from one or more plants are used):<\/li>\n<li>Formula used (if a phytocomplex from a formula is used):<\/li>\n<li>Purified molecules used (if single compounds are used): loganin, ursolic acid<\/li>\n<li>Disease\/s: diabetes<\/li>\n<li>molecular target\/s and\/or mechanisms investigated: reduced PEPCK gene expression for hepatic gluconeogenesis, \u03b2-cell protection against toxic challenge, insulin secretion enhancement in hyperglycemic condition<\/li>\n<li>General quality score (mean \u00b1 SD): 52 \u00b111<\/li>\n<li>Relevance score for TCM research (mean \u00b1 SD): 4,6 \u00b11,5<\/li>\n<\/ul>\n<p><\/p>","protected":false},"excerpt":{"rendered":"<p>Article (title, authors, journal, year and pages):\u00a0Fructus Corni suppresses hepatic gluconeogenesis related gene transcription,enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death\u00a0\u2013 Chen CC et al. &#8211; [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"categories":[87],"tags":[],"class_list":["post-3090","post","type-post","status-publish","format-standard","hentry","category-member-area","et-doesnt-have-format-content","et_post_format-et-post-format-standard"],"_links":{"self":[{"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/posts\/3090","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/comments?post=3090"}],"version-history":[{"count":1,"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/posts\/3090\/revisions"}],"predecessor-version":[{"id":3100,"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/posts\/3090\/revisions\/3100"}],"wp:attachment":[{"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/media?parent=3090"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/categories?post=3090"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.gp-tcm.org\/index.php\/wp-json\/wp\/v2\/tags?post=3090"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}