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(English) WP4 will discuss if therapeutic efficacy of herbal medicines can be screened in innovative in silico models or cell-based models of diseases, through applying functional genomics and bioinformatics techniques. Since functional genomics strategy has the capacity to provide a whole picture of the changes at the molecular level, it will also be discussed whether the mechanisms of action of CHM can be better explained by using these high-throughput assays. By combining the activity assays and high-throughput full-profile molecular assays, it will also be of interest to see if new series of therapeutic targets can be discovered. This will link the holistic TCM approach back to a more conventional research strategy so that these two can work effectively …more